Search results for "syndrome scale panss"

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FOXP2 expression and gray matter density in the male brains of patients with schizophrenia

2021

Common genetic variants ofFOXP2may contribute to schizophrenia vulnerability, but controversial results have been reported for this proposal. Here we evaluated the potential impact of the commonFOXP2rs2396753 polymorphism in schizophrenia. It was previously reported to be part of a risk haplotype for this disease and to have significant effects on gray matter concentration in the patients. We undertook the first examination into whether rs2396753 affects the brain expression ofFOXP2and a replication study of earlier neuroimaging findings of the influence of this genetic variant on brain structure.FOXP2expression levels were measured in postmortem prefrontal cortex samples of 84 male subject…

MaleCandidate geneSistema nerviós central MalaltiesFOXP2Cognitive NeurosciencePhysiologyBiology03 medical and health sciencesBehavioral NeuroscienceCellular and Molecular NeuroscienceMagnetic resonance imaging0302 clinical medicinemaleNeuroimagingexpressionGenetic variationmedicinemagnetic resonance imagingHumansRadiology Nuclear Medicine and imagingGray MatterPrefrontal cortexOriginal ResearchCerebral Cortexmedicine.diagnostic_testlanguage lateralizationsevere speechBrain morphometrysyndrome scale panssassociationNeuropsychologyBrainForkhead Transcription FactorsMagnetic resonance imagingFOXP2gray matterdisorder030227 psychiatryschizophreniaPsychiatry and Mental healthNeurologySchizophreniaEsquizofrèniagenetic-variationNeurology (clinical)polymorphisms030217 neurology & neurosurgeryBrain Imaging and Behavior
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